Exploiting the potential of natural compounds:
Myxobacteria as source for therapeutic leads and chemical tools in cancer research
Prof. Dr. Angelika M. Vollmar (Speaker)
Prof. Dr. Rolf Müller (Deputy Speaker)
Natural products play an important role in drug discovery and biomedical research for two major reasons:
1. They possess an enormous structural diversity serving as privileged scaffolds in drug discovery (leads) and
2. They have proven to be valuable tools for examining cellular processes and identifying targets in signal transduction pathways.
However, besides this enormous potential of natural products, obstacles exist. These are mainly due to difficulties in isolation and/or synthesis in sufficient quantities and, consequently, to a lack of thorough investigations concerning their molecular mechanisms of action and their targets.
Clearly, the potential of natural products in pharmaceutical sciences is not yet fully exploited.
Technische Universität München, Johann Wolfgang Goethe Universität Frankfurt, Friedrich-Schiller-Universiät Jena, Helmholtz Institute for Pharmaceutical Research Saarland, Universität des Saarlandes Saarbrücken, Universität Bonn, Ludwig-Maximilians-Unversität München